NADPH oxidase expression and production of superoxide by human corneal stromal cells

@inproceedings{OBrien2009NADPHOE,
  title={NADPH oxidase expression and production of superoxide by human corneal stromal cells},
  author={William J. O’Brien and Tom Heimann and Farhan Rizvi},
  booktitle={Molecular vision},
  year={2009}
}
PURPOSE Superoxide (O(2) (.-)) may function as a second messenger or regulator of signal transduction when produced at low concentrations in the proper locations within cells. The purpose of these studies was to determine whether human corneal stromal (HCS) fibroblasts are capable of producing O(2) (.-) via nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, a family of protein complexes believed to be responsible for the localized and limited production of O(2) (.-) with regulatory… CONTINUE READING
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Biological roles for the NOX family NADPH oxidases.

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