NADPH oxidase enzymes in skin fibrosis: molecular targets and therapeutic agents

@article{Babalola2013NADPHOE,
  title={NADPH oxidase enzymes in skin fibrosis: molecular targets and therapeutic agents},
  author={Olubukola Babalola and Andrew Mamalis and Hadar A Lev-Tov and Jared R. Jagdeo},
  journal={Archives of Dermatological Research},
  year={2013},
  volume={306},
  pages={313-330}
}
Fibrosis is characterized by the excessive deposition of extracellular matrix components eventually resulting in organ dysfunction and failure. In dermatology, fibrosis is the hallmark component of many skin diseases, including systemic sclerosis, graft-versus-host disease, hypertrophic scars, keloids, nephrogenic systemic fibrosis, porphyria cutanea tarda, restrictive dermopathy and other conditions. Fibrotic skin disorders may be debilitating and impair quality of life. There are few FDA… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 125 references

NOX enzymes as novel targets for drug development

Seminars in Immunopathology • 2008
View 10 Excerpts
Highly Influenced

Aiding and abetting roles of NOX oxidases in cellular transformation

Nature Reviews Cancer • 2012
View 11 Excerpts
Highly Influenced

Scleroderma. In: Fitzpatrick’s Dermatology in general medicine, 8th edn

P Moinzadeh, C Denton, T Krieg, C Black
2012
View 4 Excerpts
Highly Influenced

The bleomycin-induced scleroderma model: what have we learned for scleroderma pathogenesis?

Archives of Dermatological Research • 2005
View 5 Excerpts
Highly Influenced

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