NADPH oxidase-derived reactive oxygen species: involvement in vascular physiology and pathology


Reactive oxygen species (ROS) are essential mediators of normal cell physiology. However, in the last few decades, it has become evident that ROS overproduction and/or alterations of the antioxidant system associated with inflammation and metabolic dysfunction are key pathological triggers of cardiovascular disorders. NADPH oxidases (Nox) represent a class… (More)
DOI: 10.1007/s00441-010-1060-y


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