NADPH oxidase 4 mediates monocyte priming and accelerated chemotaxis induced by metabolic stress.

@article{Ullevig2012NADPHO4,
  title={NADPH oxidase 4 mediates monocyte priming and accelerated chemotaxis induced by metabolic stress.},
  author={Sarah L. Ullevig and Qingwei Zhao and Chi Fung Lee and Hong Seok Kim and Debora A. Zamora and Reto H Asmis},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2012},
  volume={32 2},
  pages={415-26}
}
OBJECTIVE Metabolic disorders increase monocyte chemoattractant protein-1 (MCP-1)-induced monocyte chemotaxis in mice. The goal of this study was to determine the molecular mechanisms responsible for the enhanced responsiveness of monocytes to chemoattractants induced by metabolic stress. METHODS AND RESULTS Chronic exposure of monocytes to diabetic… CONTINUE READING