NADPH oxidase (CYBA) and FcgammaR polymorphisms as risk factors for aggressive periodontitis: a case-control association study.

@article{Nibali2006NADPHO,
  title={NADPH oxidase (CYBA) and FcgammaR polymorphisms as risk factors for aggressive periodontitis: a case-control association study.},
  author={Luigi Nibali and Mohamed H. Parkar and Peter M. Brett and Jackie Knight and Maurizio S Tonetti and Gareth Steven Fredericton Griffiths},
  journal={Journal of clinical periodontology},
  year={2006},
  volume={33 8},
  pages={
          529-39
        }
}
INTRODUCTION Neutrophils (PMN) in aggressive periodontitis (AgP) patients have been reported to be hyperactive especially with regards to superoxide production. Polymorphisms in genes influencing PMN function have been proposed as candidate risk factors for AgP. The aim of this study was to test the association of specific gene polymorphisms affecting PMN functions with AgP. MATERIALS AND METHODS Two hundred and twenty-four patients with confirmed diagnosis of AgP and 231 subjects with… CONTINUE READING
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