NADPH-P-450 reductase: structural and functional comparisons of the eukaryotic and prokaryotic isoforms.

@article{Sevrioukova1995NADPHP450RS,
  title={NADPH-P-450 reductase: structural and functional comparisons of the eukaryotic and prokaryotic isoforms.},
  author={Irina F Sevrioukova and Julian Peterson},
  journal={Biochimie},
  year={1995},
  volume={77 7-8},
  pages={562-72}
}
The comparison of the properties of microsomal NADPH-P-450 reductase and the flavoprotein domain of P-450BM-3 (BMR) has revealed a significant difference in the mechanism of reduction of the hemoprotein P-450 by these flavoproteins. Microsomal NADPH-P-450 reductase transfers electrons to the hemoprotein by shuttling between hydroquinone and semiquinone forms of the FMN delivering one electron per cycle. Since the microsomal NADPH-P450 reductase has evolved as a component of multi-enzyme system… CONTINUE READING

From This Paper

Topics from this paper.
8 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…