NADH oxidase activity of rat and human liver xanthine oxidoreductase: potential role in superoxide production

Abstract

To characterise the NADH oxidase activity of both xanthine dehydrogenase (XD) and xanthine oxidase (XO) forms of rat liver xanthine oxidoreductase (XOR) and to evaluate the potential role of this mammalian enzyme as an O2 •− source, kinetics and electron paramagnetic resonance (EPR) spectroscopic studies were performed. A steady-state kinetics study of XD… (More)
DOI: 10.1007/s00775-007-0229-7

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Cite this paper

@article{Maia2007NADHOA, title={NADH oxidase activity of rat and human liver xanthine oxidoreductase: potential role in superoxide production}, author={Luisa B Maia and Rui Oliveira Duarte and Ana Ponces-Freire and Jos{\'e} J. G. Moura and Lurdes Mira}, journal={JBIC Journal of Biological Inorganic Chemistry}, year={2007}, volume={12}, pages={777-787} }