NADH model mediated reduction of C = N substrates : enantioselective synthesis of Dand L-phenylglycinates

@inproceedings{JozefAJ2017NADHMM,
  title={NADH model mediated reduction of C = N substrates : enantioselective synthesis of Dand L-phenylglycinates},
  author={M. JozefA.J. and Vekemans},
  year={2017}
}
  • M. JozefA.J., Vekemans
  • Published 2017
Hydride transfer from N,N, 1,2,4-pentamethyl-1,4-dihydronicotinamide, 1, to methyl 2-methoxycarbonylimino-phenylacetate, 3, was accomplished in an optical yield 2 95 %. Efficient chirality transfer from reduced NADH models to prochiral carbonyl substrates has i.a. been achieved with pentamethylated 1,4-dihydronicotinamide 1. ’ In comparison with 1,4… CONTINUE READING