NADH-dependent tiglyl-CoA reduction in disrupted mitochondria of Ascaris suum.

Abstract

The incubation of 2-methylcrotonyl-CoA with either succinate or NADH and disrupted Ascaris suum mitochondria results in substantial 2-methylbutyrate formation. Both membrane-bound and soluble components are required and the NADH-dependent reduction is rotenone sensitive, suggesting the involvement of the electron-transport chain. Rat liver mitochondria… (More)

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