NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs

@article{Cahov2015NADCI,
  title={NAD captureSeq indicates NAD as a bacterial cap for a subset of regulatory RNAs},
  author={Hana Cahov{\'a} and Marie-Luise Winz and Katharina H{\"o}fer and Gabriele N{\"u}bel and Andres J{\"a}schke},
  journal={Nature},
  year={2015},
  volume={519},
  pages={374-377}
}
A distinctive feature of prokaryotic gene expression is the absence of 5′-capped RNA. In eukaryotes, 5′,5′-triphosphate-linked 7-methylguanosine protects messenger RNA from degradation and modulates maturation, localization and translation. Recently, the cofactor nicotinamide adenine dinucleotide (NAD) was reported as a covalent modification of bacterial RNA. Given the central role of NAD in redox biochemistry, posttranslational protein modification and signalling, its attachment to RNA… 

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