NAD: a master regulator of transcription.

@article{Ghosh2010NADAM,
  title={NAD: a master regulator of transcription.},
  author={Sanchari Ghosh and Suji George and Upasana Roy and Deepti Ramachandran and Ullas Kolthur-Seetharam},
  journal={Biochimica et biophysica acta},
  year={2010},
  volume={1799 10-12},
  pages={
          681-93
        }
}
Cellular processes such as proliferation, differentiation and death are intrinsically dependent upon the redox status of a cell. Among other indicators of redox flux, cellular NAD(H) levels play a predominant role in transcriptional reprogramming. In addition to this, normal physiological functions of a cell are regulated in response to perturbations in NAD(H) levels (for example, due to alterations in diet/metabolism) to maintain homeostatic conditions. Cells achieve this homeostasis by… CONTINUE READING
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