NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport.

@article{Schlsser1993NADBT,
  title={NAD+ binding to the Escherichia coli K(+)-uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport.},
  author={Axel Schl{\"o}sser and Andrea Hamann and D Bossemeyer and Erwin Schneider and Evert P. Bakker},
  journal={Molecular microbiology},
  year={1993},
  volume={9 3},
  pages={533-43}
}
The nucleotide sequence of trkA, a gene encoding a surface component of the constitutive K(+)-uptake systems TrkG and TrkH from Escherichia coli, was determined. The structure of the TrkA protein deduced from the nucleotide sequence accords with the view that TrkA is peripherally bound to the inner side of the cytoplasmic membrane. Analysis by a dot matrix… CONTINUE READING