NACP/α-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy

@article{Arima1998NACPsynucleinII,
  title={NACP/$\alpha$-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy},
  author={Kunimasa Arima and Kenji U{\'e}da and Nobuhiko Sunohara and Kenji Arakawa and Shigeo Hirai and Minako Nakamura and Haruko Tonozuka-Uehara and Mitsuru Kawai},
  journal={Acta Neuropathologica},
  year={1998},
  volume={96},
  pages={439-444}
}
Abstract We examined neuronal cytoplasmic inclusions (NCIs) and oligodendrocytic glial cytoplasmic inclusions (GCIs) in the pontine nuclei in multiple system atrophy (MSA) using antibodies against the non-amyloid β component of Alzheimer’s disease amyloid precursor protein (NACP/α-synuclein). Our immunohistochemical study revealed that anti-NACP antibodies labeled both NCIs and GCIs. Immunoelectron microscopy showed that positive reaction products were localized on the 15- to 30-nm-thick… 

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