NACA is a positive regulator of human erythroid-cell differentiation.

  title={NACA is a positive regulator of human erythroid-cell differentiation.},
  author={Sophie Lopez and Laetitia Stuhl and Serge Fichelson and Anne Dubart-Kupperschmitt and Ren{\'e} St Arnaud and Jes{\'u}s Galindo and Anne Murati and Nicole Berda and Patrice Dubreuil and Sophie Gomez},
  journal={Journal of cell science},
  volume={118 Pt 8},
We have previously identified the transcript encoding NACA (the alpha chain of the nascent-polypeptide-associated complex) as a cytokine-modulated specific transcript in the human TF-1 erythroleukemic cell line. This protein was already known to be a transcriptional co-activator that acts by potentiating AP-1 activity in osteoblasts, and is known to be involved in the targeting of nascent polypeptides. In this study, we investigate the role of NACA in human hematopoiesis. Protein distribution… CONTINUE READING

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FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 2009
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