N4-Behenoyl-1-beta-D-arabinofuranosylcytosine as a potential new antitumor agent.

  title={N4-Behenoyl-1-beta-D-arabinofuranosylcytosine as a potential new antitumor agent.},
  author={Minoru Aoshima and Shigeru Tsukagoshi and Yoichi Sakurai and J I Oh-ishi and Toshimasa Ishida},
  journal={Cancer research},
  volume={37 8 Pt 1},
N4-Acyl-1-beta-D-arabinofuranosylcytosines, which are lipophilic antitumor analogs of 1-beta-D-arabinofuranosylcytosine, were dissolved by the use of a detergent, HCO-60, and the differences in the antitumor activities when the drugs were administered in the forms of solution or suspension were compared. N4-Stearoyl-1-beta-D-arabinofuranosylcytosine (NSC 201290), which was the most active compound when administered as an aqueous suspension, diminished in its activities after it had been… CONTINUE READING
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