N2,N2 , 7-Trimethylguanine, a New Trimethylated Guanine Natural Product from the New Zealand Ascidian, Lissoclinum Notti

@article{Pearce2001N2N27,
  title={N2,N2 , 7-Trimethylguanine, a New Trimethylated Guanine Natural Product from the New Zealand Ascidian, Lissoclinum Notti},
  author={A. Norrie Pearce and Russell C. Babcock and Gretchen Lambert and Brent R. Copp},
  journal={Natural Product Letters},
  year={2001},
  volume={15},
  pages={237 - 241}
}
Abstract From the New Zealand ascidian, Lissoclinum notti a new natural product, N2,N2 , 7-trimethyl-guanine (1) has been isolated. The structure of 1 was elucidated by analysis of spectroscopic data. 

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References

SHOWING 1-10 OF 14 REFERENCES
Synthesen in der Purinreihe, XV1) Synthesen von Xanthinium‐ und Guaninium‐betainen
Die Synthese von 7.9-Alkyl-xanthinium- und -guaninium-betainen wird beschrieben. Ausgehend von Xanthin und Xanthin-Derivaten erhalt man mit p-Toluolsulfonsaureeestern die Tosylate, die mit Ammoniak
Primary sequence of U-1 nuclear ribonucleic acid of Novikoff hepatoma ascites cells.
TLDR
The U-1 RNA is one of the low molecular weight nuclear RNAs of Novikoff hepatoma ascites cells that is specifically localized to the extranucleolar portion of the nucleus and is an alkali-stable tetranucleotide containing N2,2,7-trimethyl guanylic acid.
Functions of the Abundant U-snRNPs
In this chapter experiments are reviewed which led from the initial hypothesis about the role of U1 snRNP in pre-mRNA splicing to the elucidation of the function of all abundant nucleoplasmic snRNPs
Methylated cap structures in eukaryotic RNAs: structure, synthesis and functions.
There are more than twenty capped small nuclear RNAs characterized in eukaryotic cells. All the capped RNAs appear to be involved in the processing of other nuclear premessenger or preribosomal RNAs.
The determinants for Sm protein binding to Xenopus U1 and U5 snRNAs are complex and non‐identical.
TLDR
Structural and sequence features unique to U1 or U5 snRNAs that contribute to common protein binding are identified and it is shown that even the most conserved features of the two RNAs are not functionally interchangeable in protein binding.
"J."
however (for it was the literal soul of the life of the Redeemer, John xv. io), is the peculiar token of fellowship with the Redeemer. That love to God (what is meant here is not God’s love to men)
Structure and Function of Major and Minor snRNPs
  • EMBO J
  • 1993
...
1
2
...