N1-acetyl-N2-formyl-5-methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant.

@article{Tan2001N1acetylN2formyl5methoxykynuramineAB,
  title={N1-acetyl-N2-formyl-5-methoxykynuramine, a biogenic amine and melatonin metabolite, functions as a potent antioxidant.},
  author={Dunxian Tan and Lucien C. Manchester and Susanne Burkhardt and Rosa M S{\'a}inz and Juan C Mayo and Ron Kohen and Esther Shohami and Yu Shu Huo and R{\"u}diger Hardeland and Russel J. Reiter},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2001},
  volume={15 12},
  pages={
          2294-6
        }
}
The biogenic amine The biogenic amine N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) was investigated for its potential antioxidative capacity. AFMK is a metabolite generated through either an enzymatic or a chemical reaction pathway from melatonin. The physiological function of AFMK remains unknown. To our knowledge, this report is the first to document the potent antioxidant action of this biogenic amine. Cyclic voltammetry (CV) shows that AFMK donates two electrons at potentials of 456 mV… CONTINUE READING
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