N-terminal tail export from the mitochondrial matrix. Adherence to the prokaryotic "positive-inside" rule of membrane protein topology.

@article{Rojo1999NterminalTE,
  title={N-terminal tail export from the mitochondrial matrix. Adherence to the prokaryotic "positive-inside" rule of membrane protein topology.},
  author={Elena E Rojo and Bernard Guiard and Walter Neupert and Rosemary A. Stuart},
  journal={The Journal of biological chemistry},
  year={1999},
  volume={274 28},
  pages={19617-22}
}
Export of N-terminal tails of mitochondrial inner membrane proteins from the mitochondrial matrix is a membrane potential-dependent process, mediated by the Oxa1p translocation machinery. The hydrophilic segments of these membrane proteins, which undergo export, display a characteristic charge profile where intermembrane space-localized segments bear a net… CONTINUE READING