N-terminal pro-brain natriuretic peptide independently predicts protein energy wasting and is associated with all-cause mortality in prevalent HD patients.

@article{Guo2009NterminalPN,
  title={N-terminal pro-brain natriuretic peptide independently predicts protein energy wasting and is associated with all-cause mortality in prevalent HD patients.},
  author={Qunying Guo and Peter Barany and Abdul Rashid Qureshi and Sunna Snaedal and Olof Heimburger and Peter Stenvinkel and Bengt Lindholm and Jonas Axelsson},
  journal={American journal of nephrology},
  year={2009},
  volume={29 6},
  pages={
          516-23
        }
}
BACKGROUND N-terminal pro-brain natriuretic peptide (NT-proBNP) has been demonstrated to be associated with cardiovascular disease (CVD) and mortality in end-stage renal disease patients. We hypothesized that common confounders, such as protein-energy wasting (PEW) and inflammation could modulate this relationship. METHODS NT-proBNP was measured in 222 prevalent hemodialysis (HD) patients (55.4% male, mean age 66 years, range 51-74) using commercial ELISA. Levels were related to clinical… CONTINUE READING
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