N-terminal fragment of the anti-angiogenic human endostatin binds copper(II) with very high affinity.

Abstract

A histidine-rich peptide HSHRDFQPVLHL-NH(2) (L), identical with the N-terminal fragment of the anti-angiogenic human endostatin has been synthesized. Endostatin is a recently identified broad spectrum angiogenesis inhibitor, which inhibits 65 different tumor types. The N-terminal 25-mer peptide fragment of human endostatin has the same antitumor effect as… (More)
DOI: 10.1016/j.jinorgbio.2009.04.006

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Cite this paper

@article{Kolozsi2009NterminalFO, title={N-terminal fragment of the anti-angiogenic human endostatin binds copper(II) with very high affinity.}, author={Andr{\'a}s Kolozsi and Attila Jancs{\'o} and N{\'o}ra Veronika Nagy and Tam{\'a}s Gajda}, journal={Journal of inorganic biochemistry}, year={2009}, volume={103 7}, pages={940-7} }