N-terminal domain of the dual-targeted pea glutathione reductase signal peptide controls organellar targeting efficiency.

Import of nuclear-encoded proteins into mitochondria and chloroplasts is generally organelle specific and its specificity depends on the N-terminal signal peptide. Yet, a group of proteins known as dual-targeted proteins have a targeting peptide capable of leading the mature protein to both organelles. We have investigated the domain structure of the dual… CONTINUE READING