• Corpus ID: 16656144

N-sulfonylpyrimidine derivatives and hyperthermia treatment of anaplastic mammary carcinoma in vivo.

@article{Pavlak2010NsulfonylpyrimidineDA,
  title={N-sulfonylpyrimidine derivatives and hyperthermia treatment of anaplastic mammary carcinoma in vivo.},
  author={Marina Pavlak and Marko Rada{\vc}i{\'c} and Ranko Stojkovi{\'c} and Biserka Žini{\'c}},
  journal={Veterinarski Arhiv},
  year={2010},
  volume={80},
  pages={311-321}
}
The aim of this study was to investigate in vivo antitumor activity of newly synthesized N-sulfonylpyrimidine derivatives applied as a single agent and in combination with hyperthermia (43 oC/60 min). Antitumor activity was examined for: 1-(p-toluenesulfonyl)cytosine (4H), 1-(p-toluenesulfonyl)cytosine hydrochloride (4HxHCl), complex (Zn(II) [1-(p-toluenesulfonyl)cytosine]2) (4K) and 5-bromo-1-(methanesulfonyl)uracil (8H). In the study was used transplantable anaplastic mammary carcinoma (AMCa… 
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