N-succinyl chitosan as buccal penetration enhancer for delivery of herbal agents in treatment of oral mucositis.

@article{Dhawan2014NsuccinylCA,
  title={N-succinyl chitosan as buccal penetration enhancer for delivery of herbal agents in treatment of oral mucositis.},
  author={Neha Dhawan and Krishan Kumar and A. Kalia and Saahil Arora},
  journal={Current drug delivery},
  year={2014},
  volume={11 3},
  pages={
          415-25
        }
}
Oral mucositis is one of the major side effects of cancer chemotherapy (30-76%) and radiotherapy (over 50%). Current palliative treatments of oral mucositis include specialized agents like pelifermin, platelet derived factors etc. or oral hygienic agents which suffered from various drawbacks like systemic side effect, least effect owing to fast wash out of buccal mucosa, patient unfriendly delivery systems, and mere symptomatic relief. In this research work, N-succinyl chitosan gel delivery… Expand