N-n-propyl-norapomorphine: An extremely potent stimulant of dopamine autoreceptors

@article{Argiolas1982NnpropylnorapomorphineAE,
  title={N-n-propyl-norapomorphine: An extremely potent stimulant of dopamine autoreceptors},
  author={Antonio Argiolas and Giampaolo Mereu and Gino Serra and M. R. Melis and Fabio Fadda and Gian Luigi Gessa},
  journal={Brain Research},
  year={1982},
  volume={231},
  pages={109-116}
}
Dopamine agonist treatment of schizophrenia with N-propylnorapomorphine.
TLDR
Observations suggest a rapid-onset tolerance phenomenon of psychosis to N-propylnorapomorphine and are consistent with results from preclinical experiments, and support the idea that the acute antipsychotic response of DA agonists is mediated by the DA autoreceptor.
Behavioral effects of apomorphine isomers in the rat: Selective locomotor-inhibitory effects of S(+)N-n-propylnorapomorphine
TLDR
The results suggest that S(+)NPA or its congeners and analogs may have selective antidopaminergic actions in limbic rather than striatal areas of mammalian brain.
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