N-myc regulation of type I insulin-like growth factor receptor in a human neuroblastoma cell line.

@article{Chambry1999NmycRO,
  title={N-myc regulation of type I insulin-like growth factor receptor in a human neuroblastoma cell line.},
  author={D Chamb{\'e}ry and S. Mohseni-Zadeh and B de Gall{\'e} and Sylvie Babajko},
  journal={Cancer research},
  year={1999},
  volume={59 12},
  pages={2898-902}
}
Insulin-like growth factors I and II (IGF-I and IGF-II) stimulate proliferation and differentiation in many cell types, including cell lines derived from human neuroblastomas. Their effects are mediated via the IGF-I receptor (IGF-IR) that is essential for growth in these cells. Amplification of the N-myc oncogene is a marker for poor prognosis in neuroblastoma development, and it therefore seemed of interest to analyze the relationships that may exist between IGF-IR and N-myc. N-myc-deficient… CONTINUE READING
23 Citations
46 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 46 references

Similar Papers

Loading similar papers…