N-methylstreptothricin D--a new streptothricin-group antibiotic from a Streptomyces spp.

  title={N-methylstreptothricin D--a new streptothricin-group antibiotic from a Streptomyces spp.},
  author={B T Kim and J. Y. Lee and Y. Y. Lee and O Y Kim and Jieun Chu and Yang Mo Goo},
  journal={The Journal of antibiotics},
  volume={47 11},

Production of a broad spectrum streptothricin like antibiotic from halotolerant Streptomyces fimbriatus isolate G1 associated with marine sediments.

One of these isolates of genus Streptomyces, G1, when tested in vitro, was found highly active against wide range of microbes including Gram-positive, Gram-negative bacteria, and different fungal pathogens.

Identification of the streptothricin and tunicamycin biosynthetic gene clusters by genome mining in Streptomyces sp. strain fd1-xmd

A novel producer of ST and TM is described and the complete process undertaken for Streptomyces sp.

Illustrative examples of probable transfer of resistance determinants from food animals to humans: Streptothricins, glycopeptides, and colistin

Three illustrations of antimicrobial use in food animal production that has contributed to the selection—and subsequent transfer—of resistance determinants from food animals to humans are included.

Isolation, structure elucidation and antibacterial activities of streptothricin acids

Comparison of the MICs with streptothricin F and D showed that the antimicrobial activities of 1–5 were decreased significantly but varied with the structures, which is in contrast to previous studies.

Identification of Streptothricin Class Antibiotics in the Earlystage of Antibiotics Screening by Electrospray Ionization Mass Spectrometry

A facile method based on ion-pair RP-HPLC coupled with electrospray ionization tandem mass spectrometry has been established for the analysis of streptothricins in the fermentation broth of Streptomyces qinlingensis and could be used as an important de-replication method in the programs of screening novel antibiotics.

Two New Members of Streptothricin Class Antibiotics from Streptomyces qinlingensis sp. nov

Four streptothricin-group antibiotics (1~4) were isolated from the fermentation broth of Streptomyces qinlingensis sp. nov. Along with the known antibiotics streptothricins F (1) and D (3), two new

Natural guanidine derivatives.

The literature on guanidine-bearing natural products is reviewed, with emphasis on occurrence, isolation, structure determination, biosynthesis, synthesis and biological activities, with 365 references.

Astonishing diversity of natural surfactants: 4. Fatty acid amide glycosides, their analogs and derivatives

More than 200 unusual and interesting natural surfactants, including their chemical structures and biological activities, are described in this review article.

Streptothricin biosynthesis is catalyzed by enzymes related to nonribosomal peptide bond formation

In a search for strains producing biocides with a wide spectrum of activity, a new strain was isolated, and the chemical structure of the bioactive product extracted from its fermentation broth was determined to be a mixture of streptothricins.



A37812: N-methylstreptothricin F.

A37812, a new member of the streptothricin class of antibiotics, has been isolated and characterized as N-methylstreptothricin F. The structure elucidation of A37812 is based on results from 13C and

The structures of component A1 (= LL-AB664) and component A2 (= LL-AC541), streptothricin-like antibiotics.

Two streptothricin-like antibiotics effective against Serratia marcescens, tentatively designated as components A1 and A2, were isolated from broth filtrate of Streptoverticillium olivoreticuli to determine the location of the carbamoyl group on the aminosugar.

A streptothricin-like antibiotic mixture, A-269A (and A-269A').

The characterization of the producer, and the production, isolation, physico-chemical properties and biological properties of A-269A are reported.

New streptothricin-group antibiotics, AN-201 I, II and III. II. Chemical structures.

The new antibiotics AN-201 I, II and III were found to be produced by a soil actinomycete identified as Streptomyces nojiriensis C-13 and identified as N beta-acetylated derivatives of streptothricins E, D and F.