N-methyl-d-aspartate enhancement of phasic responses in primate neocortex

@article{Schroeder1997NmethyldaspartateEO,
  title={N-methyl-d-aspartate enhancement of phasic responses in primate neocortex},
  author={Charles E. Schroeder and Daniel C. Javitt and Mitchell Steinschneider and Ashesh D. Mehta and Syndee J Givre and Herbert G. Vaughan and Joseph C. Arezzo},
  journal={Experimental Brain Research},
  year={1997},
  volume={114},
  pages={271-278}
}
 In area 17 of the awake macaque, disinhibition by blockade of GABAA receptors results in a marked elevation in neuronal excitability, with a particular focus in the supragranular laminae. We examined the possibility that the excitatory supragranular response is N-methyl-d-aspartate (NMDA)-mediated. Laminar activity profiles consisting of flash-evoked field potential, current source density (CSD) and multiunit activity (MUA) measures were obtained during striate cortex penetrations using… CONTINUE READING
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