N-methyl-D-aspartate receptor subunit changes after traumatic injury to the developing brain.

@article{Giza2006NmethylDaspartateRS,
  title={N-methyl-D-aspartate receptor subunit changes after traumatic injury to the developing brain.},
  author={Christopher C. Giza and Naomi S Santa Maria and David A. Hovda},
  journal={Journal of neurotrauma},
  year={2006},
  volume={23 6},
  pages={
          950-61
        }
}
Traumatic brain injury (TBI) is a major cause of disability in the pediatric population and can result in abnormal development. Experimental studies conducted in animals have revealed impaired plasticity following developmental TBI, even in the absence of significant anatomical damage. The N-methyl-D-aspartate receptor (NMDAR) is clearly involved in both normal development and in the pathophysiology of TBI. Following lateral fluid percussion injury in postnatal day (PND) 19 rats, we tested the… CONTINUE READING
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