N-methyl-D-aspartate receptor encephalitis: laboratory diagnostics and comparative clinical features in adults and children.

@article{Gastaldi2018NmethylDaspartateRE,
  title={N-methyl-D-aspartate receptor encephalitis: laboratory diagnostics and comparative clinical features in adults and children.},
  author={Matteo Gastaldi and Margherita Nosadini and Marianna Spatola and Stefano Sartori and Diego Franciotta},
  journal={Expert review of molecular diagnostics},
  year={2018},
  volume={18 2},
  pages={
          181-193
        }
}
INTRODUCTION N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most common autoimmune encephalitis due to autoantibodies against neuronal surface antigens, can affect both children and adults, leading to neurological and neuropsychological sequelae. However, it is potentially treatable and the prompt start of immunotherapy associates with better prognosis. Conversely, misdiagnosis can be harmful. The detection of NMDAR antibodies in serum and cerebrospinal fluid plays a pivotal role in… CONTINUE READING
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