N-methyl-D-aspartate antagonist applied to the spinal cord hindlimb enlargement reduces the amplitude of flexion reflex in the turtle.

@article{Stein1989NmethylDaspartateAA,
  title={N-methyl-D-aspartate antagonist applied to the spinal cord hindlimb enlargement reduces the amplitude of flexion reflex in the turtle.},
  author={Paul S G Stein and Cora Schild},
  journal={Brain research},
  year={1989},
  volume={479 2},
  pages={379-83}
}
APV (D(-)-2-amino-5-phosphonovalerate), an NMDA (N-methyl-D-aspartate) antagonist, was applied in situ onto segments of the hindlimb enlargement of the turtle spinal cord. APV reduced the response amplitude of the flexion reflex. In contrast, APV did not alter the responsiveness of the rostral scratch reflex. Afferents for the flexion reflex enter the spinal cord via the dorsal roots of the middle segment of the hindlimb enlargement; afferents for the rostral scratch reflex enter the spinal… CONTINUE READING

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