N-methyl D-aspartate (NMDA) evoked changes in blood pressure and heart rate from the rat superior colliculus

@article{Keay1990NmethylD,
  title={N-methyl D-aspartate (NMDA) evoked changes in blood pressure and heart rate from the rat superior colliculus},
  author={Kevin A Keay and Paul Dean and Peter Redgrave},
  journal={Experimental Brain Research},
  year={1990},
  volume={80},
  pages={148-156}
}
Electrical stimulation and microinjections of the GABA antagonist bicuculline methiodide into the superior colliculus (SC) of the anaesthetized rat can evoke changes in blood pressure and heart rate. The long latency of bicuculline evoked responses, however, raises the possibility that they may have been produced by the diffusion of bicuculline to surrounding tissue, in particular, the periaqueductal gray. Thus, the purpose of the present study was to investigate whether such changes could have… CONTINUE READING