N-glycosylation and residue 96 are involved in the functional properties of UDP-glucuronosyltransferase enzymes.

@article{Barbier2000NglycosylationAR,
  title={N-glycosylation and residue 96 are involved in the functional properties of UDP-glucuronosyltransferase enzymes.},
  author={Olivier Barbier and Caroline Girard and Rock Breton and Alain B{\'e}langer and Dean W. Hum},
  journal={Biochemistry},
  year={2000},
  volume={39 38},
  pages={11540-52}
}
The recent cloning of several human and monkey UDP-glucuronosyltransferase (UGT) 2B proteins has allowed the characterization of these steroid metabolic enzymes. However, relatively little is known about the structure-function relationship, and the potential post-translational modifications of these proteins. The mammalian UGT2B proteins contain at least one consensus asparagine-linked glycosylation site NX(S/T). Endoglycosidase H digestion of the human and monkey UGT2B proteins demonstrates… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…