N-cadherin mediated distribution of beta-catenin alters MAP kinase and BMP-2 signaling on chondrogenesis-related gene expression.

@article{Modarresi2005NcadherinMD,
  title={N-cadherin mediated distribution of beta-catenin alters MAP kinase and BMP-2 signaling on chondrogenesis-related gene expression.},
  author={Rozbeh Modarresi and Toulouse Lafond and Jorge A. Rom{\'a}n-Blas and K G Keith G Danielson and Rocky S Tuan and Mohamad Seghatoleslami},
  journal={Journal of cellular biochemistry},
  year={2005},
  volume={95 1},
  pages={53-63}
}
We have examined the effect of calcium-dependent adhesion, mediated by N-cadherin, on cell signaling during chondrogenesis of multipotential embryonic mouse C3H10T1/2 cells. The activity of chondrogenic genes, type II collagen, aggrecan, and Sox9 were examined in monolayer (non-chondrogenic), and micromass (chondrogenic) cultures of parental C3H10T1/2 cells… CONTINUE READING