N-cadherin and β1-integrins cooperate during the development of the enteric nervous system.

@article{BrodersBondon2012NcadherinA,
  title={N-cadherin and β1-integrins cooperate during the development of the enteric nervous system.},
  author={Florence Broders-Bondon and Perrine Paul-Gilloteaux and Camille Carlier and Glenn L Radice and Sylvie Dufour},
  journal={Developmental biology},
  year={2012},
  volume={364 2},
  pages={
          178-91
        }
}
Cell adhesion controls various embryonic morphogenetic processes, including the development of the enteric nervous system (ENS). Ablation of β1-integrin (β1-/-) expression in enteric neural crest cells (ENCC) in mice leads to major alterations in the ENS structure caused by reduced migration and increased aggregation properties of ENCC during gut colonization, which gives rise to a Hirschsprung's disease-like phenotype. In the present study, we examined the role of N-cadherin in ENS development… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 74 REFERENCES

Modulation of mouse neural crest cell motility by N-cadherin and connexin 43 gap junctions

  • The Journal of cell biology
  • 2001
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Integrin structure, activation, and interactions.

  • Cold Spring Harbor perspectives in biology
  • 2011
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL