N-cadherin, a novel prognostic biomarker, drives malignant progression of colorectal cancer.

@article{Yan2015NcadherinAN,
  title={N-cadherin, a novel prognostic biomarker, drives malignant progression of colorectal cancer.},
  author={Xuebing Yan and Leilei Yan and Sihong Liu and Zezhi Shan and Yuan Tian and Zhiming Jin},
  journal={Molecular medicine reports},
  year={2015},
  volume={12 2},
  pages={2999-3006}
}
Recent studies have indicated that the epithelial-mesenchymal transition (EMT) is a key molecular mechanism involved in the development of colorectal cancer (CRC). N-cadherin is a mesenchymal marker of the EMT and has been closely linked to several human malignancies. However, its role in CRC has remained elusive. In the present study, qRT-PCR and western… CONTINUE READING