N-alkaline phosphatase: a potential disease marker for lymphoproliferative disorders.

@article{Neumann1979NalkalinePA,
  title={N-alkaline phosphatase: a potential disease marker for lymphoproliferative disorders.},
  author={Hava Neumann and Eva Klein and Robert Russell and Suzanne Epstein},
  journal={British journal of haematology},
  year={1979},
  volume={41 4},
  pages={519-32}
}
A characteristic alkaline phosphatase (orthophosphoric monoester hydrolase, alkaline pH optimum, EC 3.1.3.1) was detected in the sera of most patients with infectious mononucleosis, acute and chronic lymphatic leukaemia, non-Hodgkin's lymphoma, Burkitt's lymphoma and nasopharyngeal carcinoma. The enzyme was also present in the sera of nine out of 26 patients with cancer of the cervix. N-APase in these cases counted 30-100% of the total alkaline phosphatase activity. N-APase was absent from the… CONTINUE READING