N-acylation of ethanolamine using lipase: a chemoselective catalyst


The N-acylation of ethanolamine (2) with various fatty acids 1a-d and esters of fatty acids 1e-h using Candida antarctica B lipase (Novozym((R)) 435) are described and optimum conditions for selective N-acylation rather than O-acylation are also discussed. Microwave assisted solution phase, solid supported and conventional methods were investigated and… (More)
DOI: 10.3762/bjoc.5.10


7 Figures and Tables

Blog articles referencing this paper

Slides referencing similar topics