N-acetylcysteine partially reverses oxidative stress and apoptosis exacerbated by Mg-deficiency culturing conditions in primary cultures of rat and human hepatocytes.

@article{Martin2006NacetylcysteinePR,
  title={N-acetylcysteine partially reverses oxidative stress and apoptosis exacerbated by Mg-deficiency culturing conditions in primary cultures of rat and human hepatocytes.},
  author={H{\'e}l{\`e}ne Martin and Catherine Abadie and Bruno Heyd and Georges Mantion and Lysiane Richert and Alain Berthelot},
  journal={Journal of the American College of Nutrition},
  year={2006},
  volume={25 5},
  pages={363-9}
}
OBJECTIVE The effects of magnesium (Mg) deficiency on the rate of oxidative stress and apoptosis in primary cultures of human hepatocytes were compared to cultured rat hepatocytes. The possible reversion by N-acetylcysteine (NAC) in Mg-deficient culturing conditions was evaluated. METHODS Incubations were conducted for up to 72 h in media containing a… CONTINUE READING