N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility

@article{Dodd2008NacetylcysteineFA,
  title={N-acetylcysteine for antioxidant therapy: pharmacology and clinical utility},
  author={Seetal Dodd and Olivia M Dean and David L. Copolov and Gin S. Malhi and Michael Berk},
  journal={Expert Opinion on Biological Therapy},
  year={2008},
  volume={8},
  pages={1955 - 1962}
}
Background: Glutathione is an endogenous antioxidant and has a ubiquitous role in many of the body's defences. Treatment with N-acetylcysteine (NAC) has been shown to increase levels of glutathione. NAC has been proposed as a treatment for several illnesses. Objectives: The efficacy and tolerability of NAC was examined across a range of conditions to evaluate the evidence supporting the use of NAC for each indication. Methods: A literature search was conducted using PubMed. Information was also… Expand
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