N-acetylcysteine attenuates alcohol-induced oxidative stess in rats.

  title={N-acetylcysteine attenuates alcohol-induced oxidative stess in rats.},
  author={Reşat Ozaras and Veysel Tahan and S. Gizem Aydin and Hafize Uzun and Safiye Kaya and Hakan Senturk},
  journal={World journal of gastroenterology},
  volume={9 4},
AIM To investigate free-radical scavenger effect of n-acetylcysteine in rats intragastrically fed with ethanol. METHODS Twenty-four rats divided into three groups were fed with ethanol (6 g/kg/day, Group 1), ethanol and n-acetylcysteine (1 g/kg, Group 2), or isocaloric dextrose (control group, Group 3) for 4 weeks. Then animals were sacrificed under ether anesthesia, and intracardiac blood and liver tissues were obtained. Measurements were made in both serum and homogenized liver tissues… CONTINUE READING