N-acetylcysteine and 2-mercaptoethane sulphonate inhibit anti-pseudomonas activity of antibiotics in vitro.

H. Alfredsson; A. Malmborg; B. Strandvik

Corpus ID: 33815414

N-acetylcysteine and 2-mercaptoethane sulphonate inhibit anti-pseudomonas activity of antibiotics in vitro.

@article{Alfredsson1987NacetylcysteineA2,
  title={N-acetylcysteine and 2-mercaptoethane sulphonate inhibit anti-pseudomonas activity of antibiotics in vitro.},
  author={H. Alfredsson and A. Malmborg and B. Strandvik},
  journal={European journal of respiratory diseases},
  year={1987},
  volume={70 4},
  pages={
          213-7
        }
}

H. Alfredsson, A. Malmborg, B. Strandvik

Published 1987

Biology, Medicine

European journal of respiratory diseases

The in vitro activity against Pseudomonas aeruginosa was investigated for serial dilutions of eight anti-Pseudomonas antibiotics in combination with serial dilutions of N-acetylcysteine (NAC) and 2-mercaptoethane sulphonate (MES). The results indicated that addition of NAC and MES to the antibiotics increased the MIC values for tobramycin, netilmicin, piperacillin, azlocillin, cefsulodin, ceftazidime and imipenem but not for colistin. The decrease of MIC found in high concentrations of NAC and… CONTINUE READING

View on PubMed