N-acetylation among HIV-positive patients and patients with AIDS: when is fast, fast and slow, slow?

@article{ONeil1997NacetylationAH,
  title={N-acetylation among HIV-positive patients and patients with AIDS: when is fast, fast and slow, slow?},
  author={William M O'Neil and Brian M. Gilfix and Ann Digirolamo and Christos M. Tsoukas and Irving W Wainer},
  journal={Clinical pharmacology and therapeutics},
  year={1997},
  volume={62 3},
  pages={261-71}
}
BACKGROUND The discrepancy between genotype and expressed phenotype of the polymorphic N-acetyltransferase (NAT2) has been suggested by separate genotypic and phenotypic studies in populations with human immunodeficiency virus (HIV). Only one study has examined both genotype and phenotype in the same population, and no discrepancies were observed. METHODS In a cross-sectional study, 105 HIV-positive patients and patients with acquired immunodeficiency syndrome (AIDS) were phenotyped for NAT2… CONTINUE READING