N-WASP is required for membrane wrapping and myelination by Schwann cells

Abstract

During peripheral nerve myelination, Schwann cells sort larger axons, ensheath them, and eventually wrap their membrane to form the myelin sheath. These processes involve extensive changes in cell shape, but the exact mechanisms involved are still unknown. Neural Wiskott-Aldrich syndrome protein (N-WASP) integrates various extracellular signals to control… (More)
DOI: 10.1083/jcb.201010013

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