N-Trimethylalanine, a novel blocked N-terminal residue of Tetrahymena histone H2B.

@article{Nomoto1982NTrimethylalanineAN,
  title={N-Trimethylalanine, a novel blocked N-terminal residue of Tetrahymena histone H2B.},
  author={Minoru Nomoto and Yoshimasa Kyogoku and K Iwai},
  journal={Journal of biochemistry},
  year={1982},
  volume={92 5},
  pages={1675-8}
}
Our previous study showed that the amino acid sequence of Tetrahymena histone H2B has a blocked N-terminal residue followed by 119 amino acid residues, X-Pro-Lys.... [J. Biochem. (1982) 91, 897-904]. Now, X has been found to be N-trimethylalanine by 1H nuclear magnetic resonance spectroscopy of the isolated X-Pro-Lys and X. This identification was supported by mass spectrometry of X-Pro-Lys and by column and paper chromatography of X. This is the first time that N-terminal blocking by… CONTINUE READING