N-Myristoyltransferase isozymes exhibit differential specificity for human immunodeficiency virus type 1 Gag and Nef.

@article{Seaton2008NMyristoyltransferaseIE,
  title={N-Myristoyltransferase isozymes exhibit differential specificity for human immunodeficiency virus type 1 Gag and Nef.},
  author={Kelly E Seaton and Charles D. Smith},
  journal={The Journal of general virology},
  year={2008},
  volume={89 Pt 1},
  pages={288-96}
}
Myristoylation of the human immunodeficiency virus type 1 (HIV-1) proteins Gag and Nef by N-myristoyltransferase (NMT) is a key process in retroviral replication and virulence, yet remains incompletely characterized. Therefore, the roles of the two isozymes, NMT1 and NMT2, in myristoylating Gag and Nef were examined using biochemical and molecular… CONTINUE READING