N-Methyl-d-aspartate receptors in the retina

  title={N-Methyl-d-aspartate receptors in the retina},
  author={Yin Shen and Xiaoling Liu and Xiong-li Yang},
  journal={Molecular Neurobiology},
The vertebrate retina is a “genuine neural center” (Ramón y Cajal), in which glutamate is a major excitatory neurotransmitter. Both N-methyl-d-aspartate (NMDA) and non-NMDA receptors are expressed in the retina. Although non-NMDA receptors and/or metabotropic glutamate receptors are generally thought to be responsible for mediating the transfer of visual signals in the outer retina, there is recent evidence suggesting that NMDA receptors are also expressed in photoreceptors, as well as… CONTINUE READING