N-Methyl-D-aspartate receptor expression in the nucleus tractus solitarii and maturation of hypoxic ventilatory response in the rat.


Ventilatory responses to hypoxia are critically dependent on the activation of N-methyl-D-aspartate (NMDA) glutamate receptors in adult rats. To investigate the role of NMDA receptors during development, we measured minute ventilation (V E) in 5-d, 10-d, and 15-d-old intact, freely behaving rat pups, using whole-body plethysmography during breathing of room… (More)