N-Halo derivatives V: Comparative antimicrobial activity of soft N-chloramine systems.

Abstract

Comparative antimicrobial activity studies for certain new classes of soft N-chloramines derived from alpha-aminiisobutyric acid and 2-amino-2-methyl-1-propanol were examined using the minimum inhibitory concentration (MIC) and/or the contact germicidal efficiency (CGE) procedures. Several factors significantly aliphatic chain length in a homologous series, (b) the degree of chlorination of thenitrogen atom, (c) the solution pH, (d) the presence of a denaturant, and (e) the nature of a positive charge.

Cite this paper

@article{Kaminski1976NHaloDV, title={N-Halo derivatives V: Comparative antimicrobial activity of soft N-chloramine systems.}, author={James Kaminski and Mark M. Huycke and S H Selk and Nicholas Bodor and Takashi Higuchi}, journal={Journal of pharmaceutical sciences}, year={1976}, volume={65 12}, pages={1737-42} }