N-Glycosylation Gene DPAGT 1 Is a Target of the Wnt /-Catenin Signaling Pathway *

@inproceedings{Sengupta2010NGlycosylationGD,
  title={N-Glycosylation Gene DPAGT 1 Is a Target of the Wnt /-Catenin Signaling Pathway *},
  author={Pritam K. Sengupta and Meghan P. Bouchie and Maria A. Kukuruzinska},
  year={2010}
}
Protein N-glycosylation and the Wnt/ -catenin signaling pathways play critical roles in development and cancer. Although N-glycosylation has been shown to influence Wnt signaling through its effects on Wnt ligands, it is unclear whether theWnt/ -catenin pathway impacts proteinN-glycosylation. In this study, we show that promoters of the first N-glycosylation gene, DPAGT1, from Chinese hamster ovary (CHO), MadinDarby canine kidney (MDCK), and human epidermoid carcinoma (A253) cells contain theT… CONTINUE READING

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