N G,N G-Dimethylarginine and N G,N'G-dimethylarginine in renal insufficiency

@article{Banchaabouchi2000NGG,
  title={N G,N G-Dimethylarginine and N G,N'G-dimethylarginine in renal insufficiency},
  author={Mumna Al Banchaabouchi and Bart Marescau and Ilse Possemiers and Rudi D'hooge and Olivier Levillain and Peter Paul De Deyn},
  journal={Pfl{\"u}gers Archiv},
  year={2000},
  volume={439},
  pages={524-531}
}
Asymmetric N G,N G-dimethylarginine (ADMA) and symmetric N G,N'G-dimethylarginine (SDMA) are basic endogenous amino acids with a guanidino group. Our renal distribution study of dimethylarginines clearly indicates that, in mouse and rat, ADMA and SDMA levels are most abundant as protein-incorporated compounds (95%). ADMA represents almost 90% of this protein-incorporated dimethylarginine amount. The four zones studied (cortex, outer and inner stripe of outer medulla, inner medulla) contain more… CONTINUE READING

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Concentration of dimethyl-L-arginine in the plasma of patients with end-stage renal failure.

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